99% Purity Lorlatinib powder Pharmaceutical Grade Lorlatinib powder Raw Lorlatinib
Product Description
Product Details
Product Name |
Lorlatinib |
Appearance |
White Powder |
CAS No. |
1454846-35-5 |
MF |
C21H19FN6O2 |
Lorlatinib (PF-06463922) is a new drug under development for the sub-group of advanced non-small cell lung cancerwho are ALK or ROS1 positive and have already undergone gene treatment with drugs thatspecifically targetthis type of cancer.Lorlatinib is currently being evaluated in phase II clinical trials as an oral dose at 100 mg daily. If marketed it will becomean additional targeted treatment for this sub-group of ALKor ROS1 positive patients.
Application&Function
It is mainly targeted at patients with non-small cell lung cancer who are resistant to the first-generation ALK inhibitors crizotinib and resistant to the second-generation ALK inhibitors Ceritinib and Alectinib.
Laroratinib (PF-06463922) is an ALK inhibitor modified from Crizotinib, which entered clinical trials in 2014 for the treatment of Chemicalbook lung cancer.It is mainly targeted at patients with non-small cell lung cancer who are resistant to the first-generation ALK inhibitors crizotinib and resistant to the second-generation ALK inhibitors Ceritinib and Alectinib.
Specification