Wholesale Selamectin Raw Material Selamectin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: D-sung Selamectin
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Selamectin
• Name: Selamectin Powder
• Assay: HPLC 99%
• Appearance: White Powder
• Color: White
• CAS No.: 220119-17-5
• Mf: C43h63no11
• MW: 769.97
• Melting Point: >180c
• Boiling Point: 917.0
• Density: 1.35
• Test Method: HPLC
• Grade: Veterinary Grade
• Application: Veterinary
• Specific: COA
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 500kg/Month

Product Description

Wholesale Selamectin Raw Material Selamectin 

Product Description

Product Details

Product Name	Selamectin
Appearance	White Powder
CAS No.	220119-17-5
MF	C43H63NO11
MW	769.97

The mechanism of action of Seramycin is the same as other avermectin drugs. On the one hand, it can act as an agonist of gamma aminobutyric acid (GABA) to trigger the release of presynaptic GABA, thereby increasing membrane permeability to Cl ¯. On the other hand, the drug can open the chloride ion channel controlled by glutamate, increasing Cl ¯ permeability and causing membrane potential hyperpolarization, thereby blocking the transmission of nerve signals and causing rapid, lethal, and non spastic neuromuscular paralysis and death of the parasite. Due to the lack of GABA neurotransmitter and glutamate controlled Cl ¯ channels in flukes and tapeworms, these drugs have no killing effect on them. The drug binding sites of invertebrates are in peripheral tissues, while those of mammals are in the central nervous system. Due to the blood-brain barrier, these drugs rarely enter brain tissues, making them safe for the vast majority of mammals.

Application&Function

Silamycin interferes with the chloride ion channels controlled by glutamate in the insect body, causing rapid, lethal, and non spasmodic neuromuscular paralysis. It has killing activity against parasites in vivo (nematodes) and in vitro (arthropods). After using this product on the skin of dogs and cats, the drug is absorbed into the bloodstream through the skin, and some of the drug enters the digestive tract and bloodstream through the mouth during animal grooming. Pharmacokinetic studies have shown that after topical application, the plasma of saikinin exhibits persistent absorption. The experimental data shows that the skin (especially sebaceous glands) is a site of accumulation of saikinin, which ensures that there is a drug concentration on the fur that can kill parasites for a longer period of time,
The safety of Seramycin has been greatly improved, with good oral and injection effects. It is an in vitro and in vivo insecticide mainly targeting adult fleas, silkworms, and scabies in pets such as cats and dogs.

Specification