Raw Materials CAS 104987-11-3 Tacrolimus Purity Tacrolimus Powder Pharmaceutical Tacrolimus

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: D-sung Tacrolimus
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Tacrolimus
• Name: Tacrolimus Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical;Immunosuppressive
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 104987-11-3
• Mf: C44h69no12
• MW: 804.031
• Boiling Point: 871.7 °c at 760 Mmhg
• Density: 1.19
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 500kg/Month

Product Description

Raw Materials CAS 104987-11-3 Tacrolimus Purity Tacrolimus Powder Pharmaceutical Tacrolimus

Product Description

Product Details

Product name	Tacrolimus
Cas number	104987-11-3
Appearance	White powder
MF	C44H69NO12
MW	804.031

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug.It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.

Application&Function

1. Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant.
2. Tacrolimus is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. 
3. Tacrolimus can be combined with steroids, azathioprine (Imuran Azasan) or mycophenolate mofetil (CellCept.

Specification