Raw Material Cilnidipine Powder 99% Purity Cilnidipine Powder Pharmaceutical Powder Cilnidipine

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung-Cilnidipine
• Product Name: Cilnidipine
• Name: Cilnidipine Powder
• Appearance: Yellow Powder
• Color: Yellow Color
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Antihypertensive
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 132203-70-4
• Mf: C27h28n2o7
• MW: 492.52042
• Boiling Point: 652.6ocat760mmhg
• Density: 1.24
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 5000kg/Month

Product Description

Raw material Cilnidipine powder 99% Purity Cilnidipine Powder Pharmaceutical Powder Cilnidipine

Product Description

Product Details

Product name	Cilnidipine
Appearance	Yellow powder
CAS NO.	132203-70-4
MF	C27H28N2O7
MW	492.52042

Cilnidipine is a calcium channel blocker. Cilnidipine is the novel calcium antagonist accompanied with L-type and N-type calcium channel blocking function. Japan and approved to come into market for the first time and used for high blood pressure treatment in 1995. Compared with other calcium antagonists, cilnidipine can act on the N-type calcium channel that existing sympathetic nerve end besides acting on L-type calcium channel that similar to most of the calcium antagonists.

Cilnidipine is a dual L-/N-type calcium channel protein inhibitor and blocker. Cilnidipine has displayed renal and vascularprotective effects and improved baroreflex sensitivity in patients with hypertension. It has also demonstrated neuroprotective effects in a rat focal brain ischemia model by removing free radicals and activating the phosphatidylinositol 3-kinase pathway.

Application&Function

Cilnidipine is a dihydropyridine calcium antagonist introduced for the treatment of essential and severe hypertension and hypertension associated with renopathy. Cilnidipine has been demonstrated to exert a potent vasodilating effect by blocking calcium influx via dihydropyridine-sensitive, voltage-dependent calcium channels. Compared to nifedipine and nicardipine, cilnidipine is superior, especially for long-term treatment, due to its characteristics of slow onset and long duration with less cardiodepressant activity. Cilnidipine is reportedly well tolerated with low toxicity. It may also be useful in ischemic heart disease.

Specification