| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product name | Gliquidone |
| Appearance | White powder |
| CAS NO. | 33342-05-1 |
| MF | C27H33N3O6S |
| MW | 527.636 |
Gliquidone is an oral hypoglycemic agent, and was called as the second generation sulfonylurea oral hypoglycemic drug together with glyburide, gliclazide and glipizide, primarily for the treatment of non-insu lin-dependent (namely, II type) diabetes. Its mechanism of action is the same as other sulfonylurea drugs and can stimulate insu lin secretion from pancreatic β cells, and can enhance the action of ins ulin, enhance the sensitivity of tissues to ins ulin action, increase the number of insu lin receptor and strengthen post-receptor action of ins ulin. During the early phase of treatment, it is mainly used for promoting the secretion of endogenous insu lin; after a period of time of treatment, its main role is to improve the sensitivity of peripheral tissues to insu lin. Diabetic nephropathy is one of the late complications of diabetes while gliquidone is the only sulfonylurea drugs that not affected by renal function and therefore can be applied to diabetic patients with impaired renal function. It is the primary-choice of drug for the treatment of patients of non-in sulin dependent diabetes accompanied with insufficiency of renal function. Gliquidone is characterized by short duration of action and seldom undergoing of renal excretion with a small dose being able to control postprandial blood glucose.
Glipazone, an organic compound with the chemical formula C27H33N3O6S, is a hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus.
Gliquidone is an anti diabetic agent used in the treatment of hypoglycemia which leads to an increased risk in diabetic cardiovascular disease. Also used in the treatment diabetic nephropathy.
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