Pharmaceutical Grade Trilostane 99% Purity Trilostane Powder Raw Powder Trilostane

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: D-sung-Trilostane
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Trilostane Powder
• Name: Trilostane
• Appearance: White Powder
• Color: White Color
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Grade
• Specific: COA
• Test Method: HPLC
• CAS No: 13647-35-3
• MW: 329.43328
• Mf: C20h27no3
• Density: 1.25
• Melting Point: 516.5
• Boiling Point: 264
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi Xian
• Production Capacity: 5000kg/Month

Product Description

Pharmaceutical Grade Trilostane 99% Purity Trilostane Powder Raw Powder Trilostane 

Product Description

Product Datails

name	Trilostane
CAS	13647-35-3
MF	C20H27NO3
MW	329.43
EINECS	237-133-0

Trilostane can suppress cortical hormone synthesis process of 3 beta dehydrogenase, make cortisol, aldosterone synthesis reduce, clinical used in the treatment of Cushing syndrome(cortisol increase disease) and primary aldosteronism,the effect is not good than metyrapone. This product has significantly reduced blood level role, may relevant to its inhibit synthetic.

Application&Function

Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin cash, and/or vomiting.

Specification