Pharmaceutical Apixaban Purity Apixaban Powder Raw Material Apixaban

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: D-sung Apixaban
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Product Name: Apixaban
• Name: Apixaban Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical
• Specific: COA
• Test Method: HPLC
• CAS No.: 503612-47-3
• Mf: C25h25n5o4
• Melting Point: 235-238
• Boiling Point: 770.468
• MW: 459.5
• Shelf Life: 2 Years
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 1000kg/Month

Product Description

Pharmaceutical Apixaban Purity Apixaban Powder Raw Material Apixaban

Product Description

Product Details

 

Product name	Apixaban
Appearance	White powder
Cas number	503612-47-3
MF	C25H25N5O4
MW	459.506

Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with the concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.

Application&Function

Function of apixaban
1. Apixaban is used for reducing the risk of blood clots in the heart and strokes in patients with atrial fibrillation who have no problems with their heart valves (nonvalvular atrial fibrillation)
2. Apixaban used for treating and preventing deep venous thrombosis (DVT) and pulmonary embolism in patients who have undergone hip or knee replacement surgery.
Application of apixaban
1) Apixaban is factor Xa inhibitor anticoagulant indicated to reduce the risk of stroke.
2) Apixaban also have effect i systemic in patients with nonvavular atrial fibrillation.

Specification