API CAS 1038915-60-4 Niraparib Intermediate Niraparib Tosylate Monohydrate Powder Niraparib
Product Description
Product Details
Product Name |
Niraparib |
Appearance |
Off-white crystalline powder |
CAS No. |
1038915-60-4 |
MF |
C19H20N4O |
MW |
320.3883 |
Nilaparib is a polyadenosine diphosphate ribose polymerase inhibitor, which inhibits DNA repair. Its active component is free alkali, stable composition is a molecule containing water of crystallization of p-toluene sulfonic acid salt or effective component for niraparibtosylatemonohydrate hydrochloride. Niraparib is a poly ADP-ribose polymerase (PARP) inhibitor, for the maintenance treatment of adult patients with recurrent epithelial ovarian,fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy.
Application & Function
Function of Niraparib
Niraparib is an orally active small molecule PARP inhibitor developed by Tesaro to treat ovarian cancer.
The drug is approved by the US FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy.
Application of Niraparib
It is mainly used for the treatment of recurrent epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer, and maintenance treatment of adult patients who have fully or partially responded to platinum chemotherapy drugs.
Specification