Antidepressants Venlafaxine HCl 99% Purity Venlafaxine Hydrochloride Powder Venlafaxine

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Venlafaxine
• Product Name: Venlafaxine
• Name: Venlafaxine Powder
• Appearance: off-White to White Crystalline Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Antidepressants
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 93413-69-5
• Mf: C17h27no2
• MW: 277.40200
• Density: 1.06 g/cm3
• Melting Point: 72-74 C
• Boiling Point: 397.6 C at 760 Mmhg
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 500kg/Month

Product Description

Antidepressants Venlafaxine Hcl 99% Purity Venlafaxine Hydrochloride Powder Venlafaxine

Product Description

Product Details

Product Name	Venlafaxine
CAS No.	93413-69-5
MF	C17H27NO2
MW	277.40200
Appearance and shape	Off-white to white crystalline powder

Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.  This means it increases the concentrations of the neurotransmitters serotonin and norepinephrine in the body and the brain.
A comparative meta-analysis of 12 major antidepressants found that venlafaxine, mirtazapine, escitalopram, and sertraline were significantly more efficacious than duloxetine, fluoxetine, fluvoxamine, paroxetine, and reboxetine.  A combination of venlafaxine and mirtazapine achieved remission rates (defined as a HAM-D score of 7 or less) of 58% in one controlled trial.  In combination with an antipsychotic medicine aripiprazole, better results in treatment resistant depression in older adults have been demonstrated.

Application & Function

Venlafaxine is used primarily for the treatment of depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms.  At low doses (<150 mg/day), it acts only on serotonergic transmission.   At moderate doses (>150 mg/day), it acts on serotonergic and noradrenergic systems, whereas at high doses (>300 mg/day), it also affects dopaminergic neurotransmission.
Due to its action on both the serotoninergic and adrenergic systems, venlafaxine is also used as a treatment to reduce episodes of cataplexy, a form of muscle weakness, in patients with the sleep disorder narcolepsy.  Some open-label and three double-blind studies have suggested the efficacy of venlafaxine in the treatment of attention deficit-hyperactivity disorder (ADHD).  Clinical trials have found possible efficacy in those with post-traumatic stress disorder (PTSD).

Specification