| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product name | Gamithromycin |
| CAS | 145435-72-9 |
| MF | C40H76N2O12 |
| MW | 777.05 |
| Density | 1.16±0.1 g/cm3(Predicted) |
Gamithromycin is a semi-synthetic macrocyclic lactone belonging to the azalide class derived from erthyromycin, typified by azithromycin. The synthesis of gamithromycin involves a ring expansion using a Beckmann rearrangement to produce the 15-membered dibasic macrolide. Gamithromycin provides a broader spectrum of action, higher acid stability and improved bioavailability compared to older analogues of the erythromycin class and has been exclusively developed for animal health applications.
Gamithromycin has both bacteriostatic and bactericidal action,mediated through the disruption of bacterial protein synthesis.
The broad spectrum antimicrobial activity of gamithromycin includes Mannheimia haemolytica, Pasteurella multocida and Histophilus somni,the bacterial pathogens most commonly associated with Bovine Respiratory Disease (BRD).
1. A macrolide compound which is known to have antibacterial activity, and is useful in the therapy of bacterial infections in mammals. Antibiotic.
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