Raw Material Powder Ketoglutarate Acid Potassium Salt 2-Ketoglutaric Acid Powder Alpha 2-Ketoglutaric Acid
Product Description
Product Details
| Product name |
2-Ketoglutaric Acid |
| Appearance |
White powder |
| CAS NO. |
328-50-7 |
| MF |
C5H6O5 |
| BOILING POINT |
185.67°C |
α- Ketoglutaric acid( α- Ketoglutaric acid, chemical formula C5H6O5, is one of two ketone based derivatives of glutaric acid, a white fine crystalline powder. Its salts are important biological compounds.
α- Ketoglutaric acid is involved in the tricarboxylic acid cycle in organisms and is an intermediate metabolite of the tricarboxylic acid cycle. It is involved in the synthesis and energy metabolism of amino acids, vitamins, and organic acids. It can also be used as a dietary supplement and has broad application prospects.
Application & Function
α- Ketoglutarate is an important metabolic intermediate in the microbial tricarboxylic acid cycle, and is a key node connecting intracellular carbon nitrogen metabolism. It is located after isocitrate and before succinyl CoA in the cycle. At this site, the replenishment reaction can be generated through the transamination of glutamic acid α- The purpose of supplementing this intermediate metabolite with ketoglutaric acid can also be achieved through the action of glutamate dehydrogenase on glutamate.
Generate amino acids
Glutamic acid can generate glutamine under the action of glutamine synthase, which uses a molecule of ATP to produce glutamine phosphate; This intermediate product is attacked by ammonia as a nucleophilic reagent, resulting in the formation of glutamine and inorganic phosphate.
Dietary supplements
α- Ketoglutaric acid is sold as a dietary supplement under the trade name AKG or a-KG and is sold to fitness enthusiasts or bodybuilders. The seller claims that this substance can improve performance at the peak of training. The seller claims that this is based on "research indicating that excessive ammonia can bind to α- Ketoglutaric acid is taken away to reduce the numerous problems caused by ammonia poisoning. However, it showed that α- The only effective study on ketoglutarate to reduce ammonia poisoning is only for patients who have undergone hemodialysis
Specification
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