| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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| CAS NO | 9041-93-4 |
| EINECS No | 232-925-2 |
| Appearance | White powder |
| Molecular Formula | C110H168N34O46S7 |
| Storage | Keep in a cool, dry, dark location |
Bleomycin is effective for squamous cell carcinomas, including cancers of the head and neck, skin, esophagus, lungs, cervix, penis, thyroid, and malignant lymphomas. Bleomycin also has a certain effect on brain tumors, malignant melanoma, and fibrosarcoma.
Bleomycin sulfate is the sulfate salt of a complex natural product antibiotic. This compound approximates metals such as
Fe(II) which then coordinate dioxygen to generate the active species. This Bleomycin-metal-dioxygen species is capable
of inducing oxidative cleavage of the DNA backbone, leading to apoptosis. The species also degrades RNA, and has
been reported to display selectivity for RNA over DNA.
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