Raw Material Powder Cabazitaxel 99% Cabazitaxel Powder Anticancer Cabazitaxel

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Dsung-Cabazitaxel
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Cabazitaxel
• Appearance: White or off-White Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anticancer
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 183133-96-2
• Mf: C45h57no14
• MW: 835.944
• Density: 1.31
• Melting Point: 180 C(Lit.)
• Boiling Point: 870.7+-65.0 C(Predicted)
• Refractive Index: 1.592
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 500 Kg/Month

Product Description

Raw Material Powder Cabazitaxel 99% Cabazitaxel Powder Anticancer Cabazitaxel

 

Product Description

Product Details

Product Name	Cabazitaxel
Appearance	White or off-white powder
CAS No.	183133-96-2
MF	C45H57NO14
MW	835.944

Cabazitaxel for the treatment of hormone-refractory metastatic prostate cancer.    As a microtubule inhibitor, cabazitaxel differs from docetaxel because it exhibits a much weaker affinity for P-glycoprotein (P-gp), an adenosine triphosphate (ATP)-dependent drug efflux pump.    Cancer cells that express P-gp become resistant to taxanes, and the effectiveness of docetaxel can be limited by its high substrate affinity for P-gp.    Clinical studies confirmed that cabazitaxel retains activity in docetaxel-resistant tumors.    Common adverse events with cabazitaxel include diarrhea and neutropenia.    Cabazitaxel in combination with predni sone is an important new treatment option for men with docetaxel-refractory metastatic CRPC (castration-resistant prostate cancer).

Application & Function

Cabazitaxel in combination is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment.
Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs.    Cabazitaxel through binding to tubulin, promoting their assembly into microtubules, and can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.
1.   Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs.
2.   Cabazitaxel through binding to tubulin, promoting their assembly into microtubules.
3.   It can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.

Specification