Pharmaceutical Intermediate Diltiazem HCl Raw Material Diltiazem Hydrochloride Powder Purity Diltiazem

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Dsung-Diltiazem
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Diltiazem
• Name: Diltiazem Powder
• Appearance: White or off-White Crystalline Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Intermediate
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 42399-41-7
• Mf: C22h26n2o4s
• MW: 414.51784
• Density: 1.26
• Melting Point: 187-188 C
• Boiling Point: 594.4 C at 760 Mmhg
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 5 Ton/Month

Product Description

Pharmaceutical Intermediate Diltiazem Hcl Raw Material Diltiazem Hydrochloride Powder Purity Diltiazem

 

Product Description

Product Details

Product Name	Diltiazem
CAS No.	42399-41-7
MF	C22H26N2O4S
MW	414.51784
Appearance and shape	White or off-white crystalline powder

Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure. Additionally, it lowers blood pressure by acting on the heart itself to reduce the rate, strength, and conduction speed of each beat.Puhopharma specializes in controling the quality and reducing the impurities of Diltiazem HCl.

Application & Function

Function
1.It is also used off-label as an effective preventive medication for migraine. 
2.It is a class 3 antianginal drug, and a class IV antiarrhythmic.
3.Diltiazem hydrochloride is an antihypertensive and cardioprotective agent as well as a calcium channel protein inhibitor. It inhibits L-type Ca2+ channels and regulates Ca2+ release from intracellular stores in neutrophils.
Application
Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.
Chemically, it is based upon a 1,4-thiazepine ring making it a benzothiazepine-type calcium channel blocker.

Specification