Pharmaceutical Intermediate CAS 12650-69-0 Mupirocin Purity Antibiotic Mupirocin Powder Raw Material Powder Mupirocin

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: Dsung-Mupirocin
• Product Name: Mupirocin
• Name: Mupirocin Powder
• Appearance: White Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Antibiotic
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 12650-69-0
• Mf: C26h44o9
• MW: 500.62
• Density: 1.183
• Melting Point: 77-78 C
• Boiling Point: 672 C
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 5 Ton/Month

Product Description

Pharmaceutical Intermediate CAS 12650-69-0 Mupirocin Purity Antibiotic Mupirocin Powder Raw Material Powder Mupirocin

 

Product Description

Product Details

Product Name	Mupirocin
CAS No.	12650-69-0
MF	C26H44O9
MW	500.62
Appearance and shape	White powder

Mupirocin, also known as Pseudomonas aeruginosa A, is an ideal antimicrobial agent for skin surface, which was marketed by GlaxoSmithKline in 1985 under the trade name of Bactroban. The FDA approved the drug for use in the U.S. in 1987, and China approved the manufacture and sale of the drug by China-US SK in 1993. Mupirocin is mainly used for the prevention and treatment of bacterial skin infections caused by gram-positive cocci. Mupirocin is mainly used for the prevention and treatment of bacterial skin infections caused by Gram-positive cocci, such as primary skin infections like impetigo, boils and folliculitis, and secondary skin infections like eczema co-infection, ulcer co-infection and trauma co-infection. The main mechanism of antibacterial action of mupirocin is to inhibit protein synthesis in bacteria.

Application & Function

Function of Mupirocin
1. Mupirocin is a topical antibiotics. Stops the synthesis of all intracellular isoleucine-containing proteins by reversibly binding to isoleucine-transfer RNA synthase and thus preventing isoleucine participation. Used for acute primary bacterial skin infections, such as folliculitis and impetigo.
2. Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.
3. Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens, reported by Fuller et al. in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.
4. Mupirocin is an antibiotic inhibitor of isoleucyl-tRNA synthetase.
Application of Mupirocin
Mupirocin Calcium is used to treat infected cuts or wounds. It is an antibiotic that works by stopping the growth of certain bacteria.
Mupirocin is used as a topical treatment for bacterial skin infections, for example, furuncle, impetigo, open wounds, etc. It is also useful in the treatment of methicillin-resistant Staphylococcus aureus (MRSA), which is a significant cause of death in hospitalized patients having received systemic antibiotic therapy. It is suggested, however, that mupirocin cannot be used for extended periods of time, or indiscriminately, as resistance does develop, and could, if it becomes widespread, destroy mupirocin's value as a treatment for MRSA. It may also result in overgrowth of non-susceptible organisms.

Specification