| Customization: | Available |
|---|---|
| CAS No.: | 57-88-5 |
| Formula: | C27h46o |
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| Product name | Cholesterol |
| Cas number | 57-88-5 |
| Apperance | White powder |
| MF | C27H46O |
| MW | 386.65354 |
Cholesterol generally refers to total cholesterol. Total cholesterol is the sum of cholesterol contained in various lipoproteins in the blood, cholesterol is the main component of cell membrane, but also the synthesis of adrenocortical hormones, sex hormones, bile acids and vitamin D and other physiological active substances important raw materials. The concentration of total cholesterol in human blood can be used as an indicator of lipid metabolism to assess the risk of atherosclerosis and ischemic cardiovascular and cerebrovascular diseases.
1. Cholesterol functions as an insulating cover for the transmission of electrical impulses in the nervous tissue.
2. Cholesterol is required to build and maintain membranes; it modulates membrane fluidity over the range of physiological temperatures. The hydroxy group on cholesterol interacts with the polar head groups of the membrane phospholipids and sphingolipids, while the bulky steroid and the hydrocarbon chain are embedded in the membrane, alongside the nonpolar fatty-acid chain of the other lipids.
3. Cholesterol contributes to the decreased fluidity of the cell membrane as the molecule is in a trans conformation making all but the side chain of cholesterol rigid and planar. In this structural role, cholesterol reduces the permeability of the plasma membrane to neutral solutes, hydrogen ions, and sodium ions.
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